Publications on Understanding & Directing Cell Fate
2021:
- Wai Hon Chooi, Quanbin Dong, Jeremy Zhi Yan Low, Clement Yuen, Jiah Shin Chin, Junquan Lin, William Ong, Quan Liu, and Sing Yian Chew (2021), 'Cell Membrane-Coated Electrospun Fibers Enhance Keratinocyte Growth through Cell-Type Specific Interactions', ACS Applied Bio Materials, 4 (5), pp. 4079-4083, https://doi.org/10.1021/acsabm.1c00303doi.org/10.1002/advs.202100805
- Vincent Kwok Lim Lam, Johnny Yu Hin Wong, Sing Yian Chew, Barbara Pui Chan (2021), 'Rac1-GTPase regulates compression-induced actin protrusions (CAPs) of mesenchymal stem cells in 3D collagen micro-tissues', Biomaterials, 274, pp. 120829, https://doi.org/10.1016/j.biomaterials.2021.120829
- Nicolas Marinval and Sing Yian Chew, 'Mechanotransduction assays for neural regeneration strategies: A focus on glial cells', APL Bioengineering, https://doi.org/10.1063/5.0037814
- Po Hen Lin, Quanbin Dong and Sing Yian Chew (2021), 'Injectable hydrogels in stroke and spinal cord injury treatment: a review on hydrogel materials, cell–matrix interactions and glial involvement', Materials Advances, https://doi.org/10.1039/D0MA00732C
2020:
- J Lin, W H Chooi, W Ong, N Zhang, M E Bechler, C ffrench-Constant, S Y Chew (2020), 'Oriented and sustained protein expression on biomimicking electrospun fibers for evaluating functionality of cells', Materials Science & Engineering: C https://doi.org/10.1016/j.msec.2020.111407
- William Ong, Nicolas Marinval, Junquan Lin, Mui Hoon Nai, Yee‐Song Chong, Coline Pinese, Sreedharan Sajikumar, Chwee Teck Lim, Charles Ffrench‐Constant, Marie E. Bechler, Sing Yian Chew (2020), 'Biomimicking Fiber Platform with Tunable Stiffness to Study Mechanotransduction Reveals Stiffness Enhances Oligodendrocyte Differentiation but Impedes Myelination through YAP‐Dependent Regulation', Small, https://doi.org/10.1002/smll.202003656
2019:
- W H Chooi, S Y Chew (2019), 'Modulation of cell-cell interactions for neural tissue engineering: Potential therapeutic applications of cell adhesion molecules in nerve regeneration', Biomaterials, 197, pp. 327-344, https://doi.org/10.1016/j.biomaterials.2019.01.030
2018:
- W H Chooi, W Ong, A Murray, J Q Lin, D Nizetic, S Y Chew (2018), 'Scaffold mediated gene knockdown for neuronal differentiation of human neural progenitor cells', Biomaterials Science, 6, pp. 3019-3029, doi: 10.1039/C8BM01034J
- W Ong, J Q Lin, M E Bechler, K Wang, M F Wang, C f-C, S Y Chew (2018), 'Microfiber Drug/Gene delivery Platform for Study of Myelination', Acta Biomaterialia, 75, pp. 152-160, https://doi.org/10.1016/j.actbio.2018.06.011
- E Makhija, A Jagielska, L Zhu, A C Bost, W Ong, S Y Chew, G V Shivashankar and K J Van Vliet (2018), 'Mechanical Strain Alters Cellular and Nuclear Dynamics at Early Stages of Oligodendrocyte Differentiation', Frontiers in Cellular Neuroscience, https://doi.org/10.3389/fncel.2018.00059
2016:
- H J Diao, K Wang, H Y Long, M F Wang, S Y Chew (2016), 'Highly Fluorescent and Photostable Polymeric Nanofibers as Scaffolds for Cell Interfacing and Long-Term Tracking', Advanced Healthcare Materials, 5 (5), pp. 529-533, doi: 10.1002/adhm.201500693
2015:
- C Guetta-Terrier, P Monzo, J Zhu, H Y Long, Lakshmi Venkatraman, Y Zhou, P P Wang, S Y Chew, A Mogilner, B Ladoux, N C Gauthier (2015), 'Protrusive waves guide 3D cell migration along nanofibers', The Journal of Cell Biology, 211 (3), pp. 683-701, doi: 10.1083/jcb.201501106
- H J Diao, W C Low, R Q Lu, S Y Chew (2015), 'Topographical effects on fiber-mediated microRNA delivery to control oligodendroglial precursor cells development', Biomaterials, 70, pp. 105-114, doi: 10.1016/j.biomaterials.2015.08.029
- W C Low, P-O Rujitanaroj, D K Lee, J Kuang, P B Messersmith, J K Y Chan, S Y Chew (2015), 'Mussel-inpsired modification of nanofibers for REST siRNA delivery: Understanding the effects of gene-silencing and substrate topography on human mesenchymal stem cell neuronal commitment', Macromolecular Bioscience, 15 (10), pp. 1457-1468, doi: 10.1002/mabi.201500101
- H J Diao, W C Low, U Milberta, Q R Lu and S Y Chew (2015), 'Nanofiber-mediated microRNA delivery to enhance differentiation and maturation of oligodendroglial precursor cells', Journal of Controlled Release, 208, pp. 85-92, doi: 10.1016/j.jconrel.2015.03.005
- W W Yau, H Long, N C Gauthier, J K Chan and S Y Chew (2015), 'The effects of nanofiber diameter and orientation on siRNA uptake and gene silencing', Biomaterials, 37, pp. 94-106. doi: 10.1016/j.biomaterials.2014.10.003
2014:
- X Jiang, M H Nai, C T Lim, C Le Visage, J K Y Chan, S Y Chew (2015), 'Polysaccharide nanofibers with variable compliance for directingcell fate', Journal of Biomedical Materials Part A, 103 (3), pp. 959-968. doi: 10.1002/jbm.a.35237
- X Jiang, R Mi, A Hoke, S Y Chew (2014), 'Nanofibrous nerve conduit-enhanced peripheral nerve regeneration', J Tissue Eng Regen Med., 8 (5), pp. 377-385. doi: 10.1002/term.1531.
2013:
- W C Low, P Rujitanaroj, D K Lee, P B Messersmith, L W Stanton, E Goh and S Y Chew (2013), 'Nanofibrous scaffold-mediated REST knockdown to enhance neuronal differentiation of stem cells', Biomaterials, 34 (14), pp. 3581-3590. doi:10.1016/j.biomaterials.2013.01.093.
- W C Low, P Rujitanaroj, F Wang, J Wang and S Y Chew (2013), 'Nanofiber-mediated release of retinoic acid and brain-derived neurotrophic factor for enhanced neuronal differentiation of neural progenitor cells', Drug Delivery and Translational Research, 5, pp. 89–100. doi: 10.10_07/s13346-013-0131-5.
2012:
- H Cao, G Marcy, E L Goh, F Wang, J Wang, S Y Chew (2012), 'The effects of nanofiber topography on astrocyte behavior and gene silencing efficiency', Macromol Biosci.,12 (5), pp. 666-674,. doi: 10.1002/mabi.201100436.
- W W Yau WW, PO Rujitanaroj, L Lam, S Y Chew (2012), 'Directing stem cell fate by controlled RNA interference', Biomaterials, 33(9), pp. 2608-28. doi: 10.1016/j.biomaterials.2011.12.021.
- W C Low, W W Yau, L W Stanton, G Marcy, E L Goh, S Y Chew (2012), 'Directing neuronal differentiation of primary neural progenitor cells by gene knockdown approach', DNA Cell Biol., 31(7), pp. 1148-1160. doi: 10.1089/dna.2011.1557.
- L Shi, R Aid, C Le Visage, S Y Chew (2012), 'Biomimicking polysaccharide nanofibers promote vascular phenotypes: a potential application for vascular tissue engineering', Macromol Biosci., 12 (3), pp. 395-401. doi: 10.1002/mabi.201100336.
- T Liu, J D Houle, J Xu, B P Chan, S Y Chew (2012), 'Nanofibrous collagen nerve conduits for spinal cord repair', Tissue Eng Part A., 18 (9-10), pp. 1057-66. doi: 10.1089/ten.TEA.2011.0430.
- X Jiang, H Q Cao, L Y Shi, S Y Ng, L W Stanton, S Y Chew (2012), 'Nanofiber topography and sustained biochemical signaling enhance human mesenchymal stem cell neural commitment', Acta Biomater., 8 (3), pp. 1290-302. doi: 10.1016/j.actbio.2011.11.019.
2011:
- S Y Chew and W C Low (2011), 'Scaffold-based approach to direct stem cell neural and cardiovascular differentiation: an analysis of physical and biochemical effects', J Biomed Mater Res A., 97 (3), pp. 355-74. doi: 10.1002/jbm.a.33064.
- L Shi, C Le Visage, S Y Chew (2011), 'Long-term stabilization of polysaccharide electrospun fibres by in situ cross-linking', J Biomater Sci Polym Ed., 22 (11), pp.1459-1472. doi: 10.1163/092050610X512108.
2010:
- H Q Cao, X Jiang, C Chai, S Y Chew (2010), 'RNA interference by nanofiber-based siRNA delivery system', J Control Release, 144(2), pp. 203-212. doi: 10.1016/j.jconrel.2010.02.003.
- H Q Cao, K McHugh, S Y Chew, J M Anderson (2010), 'The topographical effect of electrospun nanofibrous scaffolds on the in vivo and in vitro foreign body reaction', J Biomed Mater Res A., 93(3), pp. 1151-1159. doi: 10.1002/jbm.a.32609.
2009 & before:
- S Y Chew , R Mi, A Hoke and K W Leong (2008), ‘The Effect of the Alignment of Electrospun Fibrous Scaffolds on Schwann Cell Maturation’, Biomaterials, 29 (6), pp. 653-661. doi: 10.1016/j.biomaterials.2007.10.025. Download.
- S Y Chew , R Mi, A Hoke and K W Leong (2007), ‘Aligned protein-polymer composite fibers enhance nerve regeneration – A potential tissue engineering platform’, Advanced Functional Materials, 17, pp. 1288-1296. doi: 10.1002/adfm.200600441. Download.