Publications on Translational Works
2023:
- Po Hen Lin, Chongquan Huang, Yuwei Hu, Vaibavi Srirangam Ramanujam, Ee-Soo Lee, Ruby Singh, Ulla Milbreta, Christine Cheung, Jackie Y. Ying, Sing Yian Chew, 'Neural cell membrane-coated DNA nanogels as a potential target-specific drug delivery tool for the central nervous system', Biomaterials, 302, pp.122325, DOI: 10.1016/j.biomaterials.2023.122325
- Christy Kwokdinata, Vaibavi Ramanujam, Jiahui Chen, Paula Nunes de Oliveira, Mui Hoon Nai, Wai Hon Chooi, Chwee Teck Lim, Shi Yan Ng, Laurent David, and Sing Yian Chew, 'Encapsulation of Human Spinal Cord Progenitor Cells in Hyaluronan-Gelatin Hydrogel for Spinal Cord Injury Treatment', ACS Applied Materials & Interfaces, 15, pp. 50679−50692, DOI: 10.1021/acsami.3c07419
2022:
- Cheryl Yi-Pin Lee, Wai Hon Chooi, Shi Yan Ng, Sing Yian Chew, 'Modulating neuroinflammation through molecular, cellular and biomaterial-based approaches to treat spinal cord injury', Bioengineering & Translational Medicine, https://doi.org/10.1002/btm2.10389
- Jiah Shin Chin, Leigh M. Madden, Anthony R. J. Philips, Sing Yian Chew, David L. Becker, 'Bio-Mimicking Acellular Wet Electrospun Scaffolds Promote Accelerated Integration and Re-Epithelialization of Full-Thickness Dermal Wounds', Bioengineering, 9 (7), 324, https://doi.org/10.3390/bioengineering9070324
- Na Zhang, Junquan Lin, Jiah Shin Chin, Christian Wiraja, Chenjie Xu, Duncan Angus McGrouther, Sing Yian Chew, 'Delivery of Wet inhibitor WIF1 via engineered polymeric microspheres promotes nerve regeneration after sciatic nerve crush', Journal of Tissue Engineering, 13, https://doi.org/10.1177/20417314221087417
2021:
- Na Zhang, Junquan Lin, Po Hen Lin, Ulla Milbreta, Jiah Shin Chin, Elaine Guo Yan Chew, Michelle Mulan Lian, Jia Nee Foo, Kunyu Zhang, Wutian Wu, Sing Yian Chew (2021), 'A 3D fiber-hydrogel based non-viral gene delivery platform reveals that microRNAs promote axon regeneration and enhance functional recovery following spinal cord injury', Advanced Science, 2100805, https://doi.org/10.1002/advs.202100805
- Po Hen Lin, Quanbin Dong and Sing Yian Chew (2021), 'Injectable hydrogels in stroke and spinal cord injury treatment: a review on hydrogel materials, cell–matrix interactions and glial involvement', Materials Advances, 2, pp. 2561-2583, https://doi.org/10.1039/D0MA00732C
2020:
- Vanja Cnops, Jiah Shin Chin, Ulla Milbreta and S Y Chew (2020), 'Biofunctional scaffolds with high packing density of aligned electrospun fibers support neural regeneration', Journal of Biomedical Materials Research, Part A, https://doi.org/10.1002/jbm.a.36998
2019:
- J Lin, I Mohamed, P H Lin, H Shirahama, U Milbreta, J L Sieow, Y Peng, M Bugiani, S C Wong, H Levinson, S Y Chew* (2019), ‘Modulating macrophage phenotype by sustained microRNA delivery improves host-implant integration’, Advanced Healthcare Materials, doi: 10.1002/adhm/201901257
- Junquan Lin, Dollaporn Anopas, Ulla Milbreta, Po Hen Lin, Jiah Shin Chin, Na Zhang, Seng Kwee Wee, Adela Tow, Wei Tech Ang, Sing Yian Chew (2019), 'Regenerative rehabilitation: Exploring the synergistic effects of rehabilitation and implantation of bio-functional scaffold in enhancing nerve regeneration', Biomaterials Science, doi: 10.1039/C9BM01095E
- Na Zhang, U Milbreta, J S Chin, C Pinese, J Q Lin, H Shirahama, W Jiang, H Liu, R Mi, A Hoke, WT Wu, S Y Chew (2019), 'Biomimicking Fiber Scaffold as an Effective In Vitro and In Vivo MicroRNA Screening Platform for Directing Tissue Regeneration', Advanced Science, https://doi.org/10.1002/advs.201800808
2018:
- U Milbreta, J Q Lin, C Pinese, W Ong, J S Chin, H Shirahama, R Mi, A Williams, M E Bechler, J Wang, C fFrench-Constant, A Hoke, S Y Chew (2018), 'Scaffold-mediated sustained, non-viral delivery of miR-219/miR-338 promotes CNS remyelination', Molecular Therapy, https://doi.org/10.1016/j.ymthe.2018.11.016
- A Dollaporn, J Q Lin, U Milbreta, V P H Lin, J S Chin, S K Wee, P E Tow, S Y Chew and W Tech Ang (2018), 'Exploring new treatment for spinalized rats by synergising robotic rehabilitation system and regenerative medicine', 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Honolulu HI, 2018, pp. 4205-4208, doi: 10.1109/EMBC.2018.8513316
- D Anopas, S Y Chew, J Q Lin, S K Wee, A Tow, W T Ang (2018), 'A Developmental Rehabilitation Robotic System for a Rat with Complete Thoracic Spinal Cord Injury in Quadruped Posture', doi: 10.1109/LRA.2018.2809596
2017:
- L H Nguyen, M Y Gao, J Q Lin, W T Wu, J Wang and S Y Chew (2017), 'Three-dimensional aligned nanofibers-hydrogel scaffold for controlled non-viral drug/gene delivery to direct axon regeneration in spinal cord injury treatment', Scientific Reports, doi: www.nature.com/articles/srep42212
2016:
- U Milbreta, L H Nguyen, H J Diao, J Q Lin, W T Wu, C-Y Sun, J Wang and S Y Chew (2016), 'Three-dimensional nanofiber hybrid scaffold directs and enhances axonal regeneration after spinal cord injury', ACS Biomaterials Science & Engineering, 2 (8), pp. 1319-1329, doi: 10.1021/acsbiomaterials.6b00248
2014:
- P Rujitanaroj, R Aid, S Y Chew* and C Le Visage (2014), 'Polysaccharide electrospun fibers with sulfated poly(fucose) promote endothelial cell migration and VEGF-mediated angiogenesis', Biomaterials Science, 2, pp. 843, 2014. (*Co-corresponding author). doi: 10.1039/C3BM60245A.
- X Jiang, R Mi, A Hoke, S Y Chew (2014), 'Nanofibrous nerve conduit-enhanced peripheral nerve regeneration', J Tissue Eng Regen Med., 8(5), pp. 377-85, 2014. doi: 10.1002/term.1531.
2013:
- P Rujitanaroj, B Jao, J Yang, J Wang, J M Anderson and S Y Chew (2013), ‘Controlling fibrous capsule formation through long-term down-regulation of collagen type I (COL1A1) expression by nanofiber-mediated gene silencing’, Acta Biomaterialia, 9 (1), p. 4513-4524. doi: 10.1016/j.actbio.2012.09029.
2012:
- T Liu, J D Houle, J Xu, B P Chan, S Y Chew (2012), 'Nanofibrous collagen nerve conduits for spinal cord repair', Tissue Eng Part A., 18(9-10), pp. 1057-66. doi: 10.1089/ten.TEA.2011.0430.
2010:
- H Q Cao, K McHugh, S Y Chew, J M Anderson (2010), 'The topographical effect of electrospun nanofibrous scaffolds on the in vivo and in vitro foreign body reaction', J Biomed Mater Res A., 93(3), pp. 1151-9. doi: 10.1002/jbm.a.32609.
2009 & before:
- S Y Chew , R Mi, A Hoke and K W Leong (2007), ‘Aligned protein-polymer composite fibers enhance nerve regeneration – A potential tissue engineering platform’, Advanced Functional Materials, 17, pp. 1288-1296. doi: 10.1002/adfm.200600441. Download.